Jonna recorded an episode of Oprah in which Dr. Pausch, a Computer Science professor suffering from terminal pancreatic cancer, gives his “farewell lecture”, apparently an exercise at the university where you give a lecture acting as if it was your last. In this case it is. Dr. Pausch provides an extremely inspirational message.
This video is basically a series of excerpts, but inspiring nonetheless.
The university has a page where you can order the lecture on DVD. You can also visit Dr. Pausch’s personal site.
Tom the Architect points to what looks like the full session from his del.icio.us links.